Notitia generali
Dapibus per Vitaminum K Absentiam seu Antagonist-II inductum (PIVKA-II), etiam ut Des-γ-carboxy-prothrombin (DCP), forma prothrombin abnormis est.Communiter, prothrombini acidi glutamici 10 residua (Glu) in acido γ-carboxyglutamico (Gla) domain in positionibus 6, 7, 14, 16, 19, 20, 25, 26, 29 et 32 γ-carboxylatae sunt ad Gla per vitaminum. -K dependens γ- glutamyl carboxylase in hepate et deinde in plasma secretae.In patientibus carcinoma hepatocellulares (HCC), γ-carboxylation prothrombin imminuitur ita ut loco prothrombin formatur PIVKA-II.PIVKA-II consideratur ut biomarki specifica efficiens pro HCC.
Patr Commendatio | CLIA (Captura-Detection): 1E5-1 ~ 1D6-10 1E5-1 ~ 1E6-7 |
Puritas | >95%, determinatum a SDS-PAGE |
Formula quiddam | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4 |
Repono | Condite eam sub conditionibus sterilibus ad -20℃ ad -80℃ acceptis. Diu terminus repone, quaeso, aliquot et repone.Vitare saepe frigore tabidaque circuitus. |
Product Name | Cattus.No | Clone ID |
PIVKA-Ⅱ | AB0009-1 | 1F4-5 |
AB0009-2 | 1E5-1 | |
AB0009-3 | 1D6-10 | |
AB0009-4 | 1E6-7 |
Nota: Bioantibody potest nativus quantitates per necessitatem tuam.
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2. Viggiani, Valentina, Palombi, .Dapibus adductus vitaminum K absentiam vel ab-amtagonistam-II (PIVKA-II) specifice auget patientibus carcinomatis Italicis hepatocellulares.[J].Acta Gastroenterologiae Scandinavian, MMXVI.
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4.Tartaglione S, Pecorella I, Zarrillo SR, et al.Dapibus inductus per Vitaminum K Absentiam II (PIVKA-II) ut biomarker potentiale serologicum in cancer pancreaticum: gubernator studentium [J].Biochemia Medica, 2019, 29(2).